Real Simple has a great collection of 18 common phrases to avoid in conversation. This post's headline -- "you're wrong!" -- is among the things you shouldn't say while fighting with your significant other.
Guilty as charged. Haha.
In all seriousness, I think I'm pretty tactful in my conversations. We all have moments of weakness, but I generally try to consider people's feelings and think before I speak.
I'm amazed by how so many people just blindly blurt things out. Don't do that. And if you do, know that your lack of tact will have consequences.
One more thing: You're wrong!